Neuronal migration anomalies are rare congenital malformations resulting from interruption of the normal proliferation and migration of neuroblasts during the third to fifth months of gestation.
The principal disorders found in this group are agyria/pachygyria complex(lissencephaly), schizencephaly, polymicrogyria, gray matter heterotopias, and unilateral megalencephaly(hemimegalencephaly).
Patients with these conditions most frequently present with developmental delay, seizures, and /or motor deficits.
In our study we found five with lissencephaly, seven with schizencephaly, seven with polymicrogyria, and eight with gray matter heterotopias in 15 patients, and neuronal migration anomalies with other anomalies were 7 patients among 15 patients.
MR imaging is sensitive to the diagnosis of these disorders because multiplanar images are easily obtained, bony artifacts are not present, and exceptional gray-white matter differentiation is inherent to MR images.
Therefore, MR imaging should be the primary imaging modality for the evaluation of children who present developmental delay, seizure and/or motor deficits.
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